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Novel indazole-based small compounds enhance TRAIL-induced apoptosis by inhibiting the MKK7-TIPRL interaction in hepatocellular carcinoma
Hepatocellular carcinoma (HCC) is one of the most malignant tumors. Although various treatments, such as surgery and chemotherapy, have been developed, a novel alternative therapeutic approach for HCC therapy is urgently needed. Tumor necrosis factor-related apoptosis inducing ligand (TRAIL) is a pr...
Autores principales: | Yoon, Ji-Yong, Lee, Jeong-Ju, Gu, Sujin, Jung, Myoung Eun, Cho, Hyun-Soo, Lim, Jung Hwa, Jun, Soo Young, Ahn, Jun-Ho, Min, Ju-Sik, Choi, Min-Hyuk, Jeon, Su-Jin, Lee, Yong-Jae, Go, Areum, Heo, Yun-Jeong, Jung, Cho-Rok, Choi, Gildon, Lee, Kwangho, Jeon, Moon-Kook, Kim, Nam-Soon |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5762535/ https://www.ncbi.nlm.nih.gov/pubmed/29348850 http://dx.doi.org/10.18632/oncotarget.22614 |
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