Protein methyltransferases and demethylases dictate CD8+ T-cell exclusion in squamous cell carcinoma of the head and neck

A subset of patients with recurrent/metastatic squamous cell carcinoma of the head and neck (SCCHN) benefit from pembrolizumab and nivolumab, but the majority of patients do not probably due to lack of activated cytotoxic CD8+ T-cells in their tumor tissues. Herein, we aim to investigate whether spe...

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Detalles Bibliográficos
Autores principales: Vougiouklakis, Theodore, Bao, Riyue, Nakamura, Yusuke, Saloura, Vassiliki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5762551/
https://www.ncbi.nlm.nih.gov/pubmed/29348866
http://dx.doi.org/10.18632/oncotarget.22627

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5762551/
https://www.ncbi.nlm.nih.gov/pubmed/29348866
http://dx.doi.org/10.18632/oncotarget.22627

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