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Role of IRF4 in resistance to immunomodulatory (IMid) compounds(®) in Waldenström’s macroglobulinemia

BACKGROUND: Immunomodulatory drugs, IMid compounds, are active in Waldenström's macroglobulinemia (WM), although in a lesser extent than multiple myeloma, where it was initially developed. We hypothesized WM tumour cells might develop mechanisms of resistance, and sought to identify and describ...

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Detalles Bibliográficos
Autores principales: Bertrand, Elisabeth, Jouy, Nathalie, Manier, Salomon, Fouquet, Guillemette, Guidez, Stéphanie, Boyle, Eileen, Noel, Stéphanie, Tomowiak, Cécile, Herbaux, Charles, Schraen, Susanna, Preudhomme, Claude, Quesnel, Bruno, Poulain, Stéphanie, Leleu, Xavier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5762562/
https://www.ncbi.nlm.nih.gov/pubmed/29348877
http://dx.doi.org/10.18632/oncotarget.22872