The potential mechanism of extracellular high mobility group box-1 protein mediated p53 expression in immune dysfunction of T lymphocytes

In the present study, we examined the activity of p53 protein in Jurkat cells treated with high mobility group box-1 protein (HMGB1), thereafter we investigated the mechanism of extracellular HMGB1 mediated p53 expression in immune dysfunction of T lymphocytes. mRNA expression of p53, mdm2, and p21...

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Detalles Bibliográficos
Autores principales: Luan, Ying-Yi, Jia, Min, Zhang, Hui, Zhu, Fu-Jun, Dong, Ning, Feng, Yong-Wen, Wu, Ming, Tong, Ya-Lin, Yao, Yong-Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5762565/
https://www.ncbi.nlm.nih.gov/pubmed/29348880
http://dx.doi.org/10.18632/oncotarget.22913

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5762565/
https://www.ncbi.nlm.nih.gov/pubmed/29348880
http://dx.doi.org/10.18632/oncotarget.22913

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