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MicroRNA203a suppresses glioma tumorigenesis through an ATM-dependent interferon response pathway

Glioblastoma (GBM) is a deadly and incurable brain tumor. Although microRNAs (miRNAs) play critical roles in regulating the cancer cell phenotype, the underlying mechanisms of how they regulate tumorigenesis are incompletely understood. We previously showed that miR-203a is expressed at relatively l...

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Detalles Bibliográficos
Autores principales: Yang, Chuan He, Wang, Yinan, Sims, Michelle, Cai, Chun, He, Ping, Häcker, Hans, Yue, Junming, Cheng, Jinjun, Boop, Frederick A., Pfeffer, Lawrence M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5762567/
https://www.ncbi.nlm.nih.gov/pubmed/29348882
http://dx.doi.org/10.18632/oncotarget.22945