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Microsatellite stability and mismatch repair proficiency in nasopharyngeal carcinoma may not predict programmed death-1 blockade resistance

The US FDA granted accelerated approval to pembrolizumab for microsatellite instability-high and mismatch repair deficient cancers. The response of programmed death-1 blockade in mismatch repair proficiency (pMMR) colorectal cancer is very poor, however, whether such treatment is effective in pMMR n...

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Detalles Bibliográficos
Autores principales: Liao, Xiyi, Zhao, Liang, Wu, Sangang, Zheng, Hua, Chen, Haojun, Zhang, Huan, Wang, ZiJing, Lin, Qin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5762592/
https://www.ncbi.nlm.nih.gov/pubmed/29348907
http://dx.doi.org/10.18632/oncotarget.22938