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Microsatellite stability and mismatch repair proficiency in nasopharyngeal carcinoma may not predict programmed death-1 blockade resistance
The US FDA granted accelerated approval to pembrolizumab for microsatellite instability-high and mismatch repair deficient cancers. The response of programmed death-1 blockade in mismatch repair proficiency (pMMR) colorectal cancer is very poor, however, whether such treatment is effective in pMMR n...
Autores principales: | Liao, Xiyi, Zhao, Liang, Wu, Sangang, Zheng, Hua, Chen, Haojun, Zhang, Huan, Wang, ZiJing, Lin, Qin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5762592/ https://www.ncbi.nlm.nih.gov/pubmed/29348907 http://dx.doi.org/10.18632/oncotarget.22938 |
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