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Determination of 6258-70, a new semi-synthetic taxane, in rat plasma and tissues: Application to the pharmacokinetics and tissue distribution study()

Cancer is the leading cause of death all over the world. Among the chemotherapy drugs, taxanes play an important role in cancer treatment. 6258-70 is a new semi-synthetic taxane which has a broad spectrum of antitumor activity. A fast and reliable high performance liquid chromatography-tandem mass s...

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Detalles Bibliográficos
Autores principales: Zhao, Simin, Zhang, Yuanyuan, Ju, Ping, Gu, Liqiang, Zhuang, Rui, Zhao, Longshan, Tang, Xing, Bi, Kaishun, Chen, Xiaohui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Xi'an Jiaotong University 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5762609/
https://www.ncbi.nlm.nih.gov/pubmed/29403986
http://dx.doi.org/10.1016/j.jpha.2016.02.003