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Domain swapping and SMYD1 interactions with the PWWP domain of human hepatoma-derived growth factor
The human hepatoma-derived growth factor (HDGF), containing the chromatin-associated N-terminal PWWP domain capable of binding the SMYD1 promoter, participates in various cellular processes and is involved in human cancers. We report the first crystal structures of the human HDGF PWWP domain (residu...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5762634/ https://www.ncbi.nlm.nih.gov/pubmed/29321480 http://dx.doi.org/10.1038/s41598-017-18510-8 |