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Domain swapping and SMYD1 interactions with the PWWP domain of human hepatoma-derived growth factor

The human hepatoma-derived growth factor (HDGF), containing the chromatin-associated N-terminal PWWP domain capable of binding the SMYD1 promoter, participates in various cellular processes and is involved in human cancers. We report the first crystal structures of the human HDGF PWWP domain (residu...

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Detalles Bibliográficos
Autores principales: Chen, Li-Ying, Huang, Yen-Chieh, Huang, Shih-Tsung, Hsieh, Yin-Cheng, Guan, Hong-Hsiang, Chen, Nai-Chi, Chuankhayan, Phimonphan, Yoshimura, Masato, Tai, Ming-Hong, Chen, Chun-Jung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5762634/
https://www.ncbi.nlm.nih.gov/pubmed/29321480
http://dx.doi.org/10.1038/s41598-017-18510-8