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Analysis of Combined Transcriptomes Identifies Gene Modules that Differentially Respond to Pathogenic Stimulation of Vascular Smooth Muscle and Endothelial Cells

Smooth muscle cells (SMCs) and endothelial cells (ECs) are vital cell types composing the vascular medial wall and the atheroprotective inner lining, respectively. Current treatments for cardiovascular disease inhibit SMC hyperplasia but compromise EC integrity, predisposing patients to thrombosis....

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Detalles Bibliográficos
Autores principales: Pan, Xiaokang, Wang, Bowen, Yuan, Tiezheng, Zhang, Mengxue, Kent, K. Craig, Guo, Lian-Wang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5762668/
https://www.ncbi.nlm.nih.gov/pubmed/29321689
http://dx.doi.org/10.1038/s41598-017-18675-2