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Blimp-1/PRDM1 is a critical regulator of Type III Interferon responses in mammary epithelial cells

The transcriptional repressor Blimp-1 originally cloned as a silencer of type I interferon (IFN)-β gene expression controls cell fate decisions in multiple tissue contexts. Conditional inactivation in the mammary gland was recently shown to disrupt epithelial cell architecture. Here we report that B...

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Detalles Bibliográficos
Autores principales: Elias, Salah, Robertson, Elizabeth J., Bikoff, Elizabeth K., Mould, Arne W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5762727/
https://www.ncbi.nlm.nih.gov/pubmed/29321612
http://dx.doi.org/10.1038/s41598-017-18652-9