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Blimp-1/PRDM1 is a critical regulator of Type III Interferon responses in mammary epithelial cells
The transcriptional repressor Blimp-1 originally cloned as a silencer of type I interferon (IFN)-β gene expression controls cell fate decisions in multiple tissue contexts. Conditional inactivation in the mammary gland was recently shown to disrupt epithelial cell architecture. Here we report that B...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5762727/ https://www.ncbi.nlm.nih.gov/pubmed/29321612 http://dx.doi.org/10.1038/s41598-017-18652-9 |