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Hypoxia Increases Thyroid Cancer Stem Cell-Enriched Side Population

INTRODUCTION: Hypoxic stress is a feature of rapidly growing thyroid tumours. Cancer progression is thought to be driven by a small population of tumour cells possessing stem cell properties. Hypoxia-inducible factors (HIFs) are important mediators of hypoxia. Both HIF-1alpha and HIF-2alpha have bee...

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Detalles Bibliográficos
Autores principales: Mahkamova, K., Latar, N., Aspinall, S., Meeson, A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5762807/
https://www.ncbi.nlm.nih.gov/pubmed/29167950
http://dx.doi.org/10.1007/s00268-017-4331-x