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A Novel Hybrid Promoter ARE-hTERT for Cancer Gene Therapy

describe a novel hybrid tumor-specific promoter, ARE-hTERT, composed of the human TERT gene promoter (hTERT) and the antioxidant response element (ARE) from the human GCLM gene promoter. The hybrid promoter retains the tumor specificity of the basal hTERT promoter but is characterized by an enhanced...

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Detalles Bibliográficos
Autores principales: Kalinichenko, S. V., Shepelev, M. V., Vikhreva, P. N., Korobko, I. V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: A.I. Gordeyev 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5762830/
https://www.ncbi.nlm.nih.gov/pubmed/29340219