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Reprogramming of pro-inflammatory human macrophages to an anti-inflammatory phenotype by bile acids

Cholestasis is caused by autoimmune reactions, drug-induced hepatotoxicity, viral infections of the liver and the obstruction of bile ducts by tumours or gallstones. Cholestatic conditions are associated with impaired innate and adaptive immunity, including alterations of the cellular functions of m...

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Detalles Bibliográficos
Autores principales: Wammers, Marianne, Schupp, Anna-Kathrin, Bode, Johannes G., Ehlting, Christian, Wolf, Stephanie, Deenen, René, Köhrer, Karl, Häussinger, Dieter, Graf, Dirk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5762890/
https://www.ncbi.nlm.nih.gov/pubmed/29321478
http://dx.doi.org/10.1038/s41598-017-18305-x