Innate IFN-γ ameliorates experimental autoimmune encephalomyelitis and promotes myeloid expansion and PDL-1 expression

The innate immune system plays a central role in the immune-mediated pathology of multiple sclerosis, and is a therapeutic target for progressive disease. Recently, it has been demonstrated that MIS416, a novel immunomodulatory microparticle that activates NOD-2 and TLR-9-signaling, has disease-modi...

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Detalles Bibliográficos
Autores principales: White, Madeleine P. J., Webster, Gill, Leonard, Faith, La Flamme, Anne Camille
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5762891/
https://www.ncbi.nlm.nih.gov/pubmed/29321652
http://dx.doi.org/10.1038/s41598-017-18543-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5762891/
https://www.ncbi.nlm.nih.gov/pubmed/29321652
http://dx.doi.org/10.1038/s41598-017-18543-z

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