Desumoylase SENP6 maintains osteochondroprogenitor homeostasis by suppressing the p53 pathway

The development, growth, and renewal of skeletal tissues rely on the function of osteochondroprogenitors (OCPs). Protein sumoylation/desumoylation has emerged as a pivotal mechanism for stem cell/progenitor homeostasis, and excessive sumoylation has been associated with cell senescence and tissue ag...

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Detalles Bibliográficos
Autores principales: Li, Jianshuang, Lu, Di, Dou, Hong, Liu, Huadie, Weaver, Kevin, Wang, Wenjun, Li, Jiada, Yeh, Edward T.H., Williams, Bart O., Zheng, Ling, Yang, Tao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5762923/
https://www.ncbi.nlm.nih.gov/pubmed/29321472
http://dx.doi.org/10.1038/s41467-017-02413-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5762923/
https://www.ncbi.nlm.nih.gov/pubmed/29321472
http://dx.doi.org/10.1038/s41467-017-02413-3

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