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Desumoylase SENP6 maintains osteochondroprogenitor homeostasis by suppressing the p53 pathway
The development, growth, and renewal of skeletal tissues rely on the function of osteochondroprogenitors (OCPs). Protein sumoylation/desumoylation has emerged as a pivotal mechanism for stem cell/progenitor homeostasis, and excessive sumoylation has been associated with cell senescence and tissue ag...
| Autores principales: | , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5762923/ https://www.ncbi.nlm.nih.gov/pubmed/29321472 http://dx.doi.org/10.1038/s41467-017-02413-3 |