Otx2-Genetically Modified Retinal Pigment Epithelial Cells Rescue Photoreceptors after Transplantation

Inherited retinal degenerations are blinding diseases characterized by the loss of photoreceptors. Their extreme genetic heterogeneity complicates treatment by gene therapy. This has motivated broader strategies for transplantation of healthy retinal pigmented epithelium to protect photoreceptors in...

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Detalles Bibliográficos
Autores principales: Kole, Christo, Klipfel, Laurence, Yang, Ying, Ferracane, Vanessa, Blond, Frederic, Reichman, Sacha, Millet-Puel, Géraldine, Clérin, Emmanuelle, Aït-Ali, Najate, Pagan, Delphine, Camara, Hawa, Delyfer, Marie-Noëlle, Nandrot, Emeline F., Sahel, Jose-Alain, Goureau, Olivier, Léveillard, Thierry
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2018
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5762984/
https://www.ncbi.nlm.nih.gov/pubmed/28988713
http://dx.doi.org/10.1016/j.ymthe.2017.09.007

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5762984/
https://www.ncbi.nlm.nih.gov/pubmed/28988713
http://dx.doi.org/10.1016/j.ymthe.2017.09.007

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