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Otx2-Genetically Modified Retinal Pigment Epithelial Cells Rescue Photoreceptors after Transplantation
Inherited retinal degenerations are blinding diseases characterized by the loss of photoreceptors. Their extreme genetic heterogeneity complicates treatment by gene therapy. This has motivated broader strategies for transplantation of healthy retinal pigmented epithelium to protect photoreceptors in...
Autores principales: | Kole, Christo, Klipfel, Laurence, Yang, Ying, Ferracane, Vanessa, Blond, Frederic, Reichman, Sacha, Millet-Puel, Géraldine, Clérin, Emmanuelle, Aït-Ali, Najate, Pagan, Delphine, Camara, Hawa, Delyfer, Marie-Noëlle, Nandrot, Emeline F., Sahel, Jose-Alain, Goureau, Olivier, Léveillard, Thierry |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society of Gene & Cell Therapy
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5762984/ https://www.ncbi.nlm.nih.gov/pubmed/28988713 http://dx.doi.org/10.1016/j.ymthe.2017.09.007 |
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