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Effects of TLR3 and TLR9 Signaling Pathway on Brain Protection in Rats Undergoing Sevoflurane Pretreatment during Cardiopulmonary Bypass

OBJECTIVE: To investigate the effects of TLR3 and TLR9 signaling pathway on brain injury during CPB in rats pretreated with sevoflurane and its possible molecular mechanism. METHODS: SD rats were randomly assigned to sham group, CPB group, and Sev group. Brain tissue was obtained at before CPB (T(0)...

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Detalles Bibliográficos
Autores principales: Nan, Zhou, Jin, Zhou, Huijuan, Cao, Tiezheng, Zhang, Keyan, Chen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5763070/
https://www.ncbi.nlm.nih.gov/pubmed/29445737
http://dx.doi.org/10.1155/2017/4286738