Failure of the PTEN/aPKC/Lgl Axis Primes Formation of Adult Brain Tumours in Drosophila

Different regions in the mammalian adult brain contain immature precursors, reinforcing the concept that brain cancers, such as glioblastoma multiforme (GBM), may originate from cells endowed with stem-like properties. Alterations of the tumour suppressor gene PTEN are very common in primary GBMs. V...

Descripción completa

Detalles Bibliográficos
Autores principales: Paglia, Simona, Sollazzo, Manuela, Di Giacomo, Simone, de Biase, Dario, Pession, Annalisa, Grifoni, Daniela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5763105/
https://www.ncbi.nlm.nih.gov/pubmed/29445734
http://dx.doi.org/10.1155/2017/2690187

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5763105/
https://www.ncbi.nlm.nih.gov/pubmed/29445734
http://dx.doi.org/10.1155/2017/2690187

Ejemplares similares