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Failure of the PTEN/aPKC/Lgl Axis Primes Formation of Adult Brain Tumours in Drosophila

Different regions in the mammalian adult brain contain immature precursors, reinforcing the concept that brain cancers, such as glioblastoma multiforme (GBM), may originate from cells endowed with stem-like properties. Alterations of the tumour suppressor gene PTEN are very common in primary GBMs. V...

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Detalles Bibliográficos
Autores principales:	Paglia, Simona, Sollazzo, Manuela, Di Giacomo, Simone, de Biase, Dario, Pession, Annalisa, Grifoni, Daniela
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5763105/ https://www.ncbi.nlm.nih.gov/pubmed/29445734 http://dx.doi.org/10.1155/2017/2690187

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