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Simvastatin Ameliorates PAK4 Inhibitor-Induced Gut and Lung Injury

P21 activated kinase 4 (PAK4), a key regulator of cytoskeletal rearrangement and endothelial microparticles (EMPs), is released after lipopolysaccharide (LPS) stimulation. In addition, it participates in LPS-induced lung injury. In this study, forty-eight Sprague Dawley (SD) rats were divided into t...

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Detalles Bibliográficos
Autores principales: Pan, Shuming, Wu, Zengbin, Liu, Xuan, Chen, Jiameng, Wang, Huiqi, Liu, Dan, Fei, Aihua, Chen, Liang, Gao, Chengjin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5763212/
https://www.ncbi.nlm.nih.gov/pubmed/29445744
http://dx.doi.org/10.1155/2017/8314276