Cigarette Smoke Exposure Inhibits Bacterial Killing via TFEB-Mediated Autophagy Impairment and Resulting Phagocytosis Defect

INTRODUCTION: Cigarette smoke (CS) exposure is the leading risk factor for COPD-emphysema pathogenesis. A common characteristic of COPD is impaired phagocytosis that causes frequent exacerbations in patients leading to increased morbidity. However, the underlying mechanism is unclear. Hence, we inve...

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Detalles Bibliográficos
Autores principales: Pehote, Garrett, Bodas, Manish, Brucia, Kathryn, Vij, Neeraj
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5763241/
https://www.ncbi.nlm.nih.gov/pubmed/29445254
http://dx.doi.org/10.1155/2017/3028082

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5763241/
https://www.ncbi.nlm.nih.gov/pubmed/29445254
http://dx.doi.org/10.1155/2017/3028082

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