Classifying cancer genome aberrations by their mutually exclusive effects on transcription

BACKGROUND: Malignant tumors are typically caused by a conglomeration of genomic aberrations—including point mutations, small insertions, small deletions, and large copy-number variations. In some cases, specific chemotherapies and targeted drug treatments are effective against tumors that harbor ce...

Descripción completa

Detalles Bibliográficos
Autores principales: Dayton, Jonathan B., Piccolo, Stephen R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5763295/
https://www.ncbi.nlm.nih.gov/pubmed/29322935
http://dx.doi.org/10.1186/s12920-017-0303-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5763295/
https://www.ncbi.nlm.nih.gov/pubmed/29322935
http://dx.doi.org/10.1186/s12920-017-0303-0

Ejemplares similares