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Classifying cancer genome aberrations by their mutually exclusive effects on transcription
BACKGROUND: Malignant tumors are typically caused by a conglomeration of genomic aberrations—including point mutations, small insertions, small deletions, and large copy-number variations. In some cases, specific chemotherapies and targeted drug treatments are effective against tumors that harbor ce...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2017
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5763295/ https://www.ncbi.nlm.nih.gov/pubmed/29322935 http://dx.doi.org/10.1186/s12920-017-0303-0 |