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A system identification approach for developing model predictive controllers of antibody quality attributes in cell culture processes

As the biopharmaceutical industry evolves to include more diverse protein formats and processes, more robust control of Critical Quality Attributes (CQAs) is needed to maintain processing flexibility without compromising quality. Active control of CQAs has been demonstrated using model predictive co...

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Detalles Bibliográficos
Autores principales: Downey, Brandon, Schmitt, John, Beller, Justin, Russell, Brian, Quach, Anthony, Hermann, Elizabeth, Lyon, David, Breit, Jeffrey
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5763414/
https://www.ncbi.nlm.nih.gov/pubmed/28786215
http://dx.doi.org/10.1002/btpr.2537