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MDD-carb: a combinatorial model for the identification of protein carbonylation sites with substrate motifs
BACKGROUND: Carbonylation, which takes place through oxidation of reactive oxygen species (ROS) on specific residues, is an irreversibly oxidative modification of proteins. It has been reported that the carbonylation is related to a number of metabolic or aging diseases including diabetes, chronic l...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5763492/ https://www.ncbi.nlm.nih.gov/pubmed/29322938 http://dx.doi.org/10.1186/s12918-017-0511-4 |