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Comparison of nuisance parameters in pediatric versus adult randomized trials: a meta-epidemiologic empirical evaluation

BACKGROUND: We wished to compare the nuisance parameters of pediatric vs. adult randomized-trials (RCTs) and determine if the latter can be used in sample size computations of the former. METHODS: In this meta-epidemiologic empirical evaluation we examined meta-analyses from the Cochrane Database of...

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Detalles Bibliográficos
Autores principales: Vandermeer, Ben, van der Tweel, Ingeborg, Jansen-van der Weide, Marijke C., Weinreich, Stephanie S., Contopoulos-Ioannidis, Despina G., Bassler, Dirk, Fernandes, Ricardo M., Askie, Lisa, Saloojee, Haroon, Baiardi, Paola, Ellenberg, Susan S., van der Lee, Johanna H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5763521/
https://www.ncbi.nlm.nih.gov/pubmed/29321002
http://dx.doi.org/10.1186/s12874-017-0456-8