Automated image analysis detects aging in clinical-grade mesenchymal stromal cell cultures

BACKGROUND: Senescent cells are undesirable in cell therapy products due to reduced therapeutic activity and risk of aberrant cellular effects, and methods for assessing senescence are needed. Early-passage mesenchymal stromal cells (MSCs) are known to be small and spindle-shaped but become enlarged...

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Detalles Bibliográficos
Autores principales: Oja, S., Komulainen, P., Penttilä, A., Nystedt, J., Korhonen, M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5763576/
https://www.ncbi.nlm.nih.gov/pubmed/29321040
http://dx.doi.org/10.1186/s13287-017-0740-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5763576/
https://www.ncbi.nlm.nih.gov/pubmed/29321040
http://dx.doi.org/10.1186/s13287-017-0740-x

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