Histone deacetylase 2 (HDAC2) attenuates lipopolysaccharide (LPS)-induced inflammation by regulating PAI-1 expression

BACKGROUND: Sepsis is a life-threatening organ dysfunction caused by dysregulated host response to infection, and is primarily characterized by an uncontrolled systemic inflammatory response. In the present study, we developed an effective adjunct therapy mediated by a novel mechanism, to attenuate...

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Detalles Bibliográficos
Autores principales: Fang, Wen-Feng, Chen, Yu-Mu, Lin, Chiung-Yu, Huang, Hui-Lin, Yeh, Hua, Chang, Ya-Ting, Huang, Kuo-Tung, Lin, Meng-Chih
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5763578/
https://www.ncbi.nlm.nih.gov/pubmed/29344006
http://dx.doi.org/10.1186/s12950-018-0179-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5763578/
https://www.ncbi.nlm.nih.gov/pubmed/29344006
http://dx.doi.org/10.1186/s12950-018-0179-6

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