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Synthesis, Cytotoxicity, and Antileishmanial Activity of N,N'-Disubstituted Ethylenediamine and Imidazolidine Derivatives

This paper describes the preparation of N,N'-disubstituted ethylenediamine and imidazolidine derivatives and their in vitro biological activities against Leishmania species. Of the nine synthesized compounds, five displayed a good activity in both L. amazonensis and L. major promastigotes. The...

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Detalles Bibliográficos
Autores principales: de Carvalho, Gustavo S. G., Machado, Patrícia A., de Paula, Daniela T. S., Coimbra, Elaine S., da Silva, Adilson D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: TheScientificWorldJOURNAL 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5763695/
https://www.ncbi.nlm.nih.gov/pubmed/20842318
http://dx.doi.org/10.1100/tsw.2010.176