Selective Inhibitors of Kv11.1 Regulate IL-6 Expression by Macrophages in Response to TLR/IL-1R Ligands

The mechanism by which the platelet-endothelial cell adhesion molecule PECAM-1 regulates leukodiapedesis, vascular endothelial integrity, and proinflammatory cytokine expression in vivo is not known. We recently identified PECAM-1 as a negative regulator of Kv11.1, a specific voltage-gated potassium...

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Detalles Bibliográficos
Autores principales: Hunter, Cheryl, Kadakia, Tejas B., Cooper, Dianne, Perretti, Mauro, Schwartz, Richard C., Brown, Simon B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: TheScientificWorldJOURNAL 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5763775/
https://www.ncbi.nlm.nih.gov/pubmed/20730378
http://dx.doi.org/10.1100/tsw.2010.155

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5763775/
https://www.ncbi.nlm.nih.gov/pubmed/20730378
http://dx.doi.org/10.1100/tsw.2010.155

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