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Selective Inhibitors of Kv11.1 Regulate IL-6 Expression by Macrophages in Response to TLR/IL-1R Ligands
The mechanism by which the platelet-endothelial cell adhesion molecule PECAM-1 regulates leukodiapedesis, vascular endothelial integrity, and proinflammatory cytokine expression in vivo is not known. We recently identified PECAM-1 as a negative regulator of Kv11.1, a specific voltage-gated potassium...
Autores principales: | Hunter, Cheryl, Kadakia, Tejas B., Cooper, Dianne, Perretti, Mauro, Schwartz, Richard C., Brown, Simon B. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
TheScientificWorldJOURNAL
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5763775/ https://www.ncbi.nlm.nih.gov/pubmed/20730378 http://dx.doi.org/10.1100/tsw.2010.155 |
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