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Role of Adenosine A(2A) Receptors in Modulating Synaptic Functions and Brain Levels of BDNF: a Possible Key Mechanism in the Pathophysiology of Huntington's Disease

In the last few years, accumulating evidence has shown the existence of an important cross-talk between adenosine A(2A) receptors (A(2A)Rs) and brain-derived neurotrophic factor (BDNF). Not only are A(2A)Rs involved in the mechanism of transactivation of BDNF receptor TrkB, they also modulate the ef...

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Detalles Bibliográficos
Autores principales: Tebano, Maria Teresa, Martire, Alberto, Chiodi, Valentina, Ferrante, Antonella, Popoli, Patrizia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: TheScientificWorldJOURNAL 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5763899/
https://www.ncbi.nlm.nih.gov/pubmed/20842321
http://dx.doi.org/10.1100/tsw.2010.164