Cargando…
Role of Adenosine A(2A) Receptors in Modulating Synaptic Functions and Brain Levels of BDNF: a Possible Key Mechanism in the Pathophysiology of Huntington's Disease
In the last few years, accumulating evidence has shown the existence of an important cross-talk between adenosine A(2A) receptors (A(2A)Rs) and brain-derived neurotrophic factor (BDNF). Not only are A(2A)Rs involved in the mechanism of transactivation of BDNF receptor TrkB, they also modulate the ef...
Autores principales: | Tebano, Maria Teresa, Martire, Alberto, Chiodi, Valentina, Ferrante, Antonella, Popoli, Patrizia |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
TheScientificWorldJOURNAL
2010
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5763899/ https://www.ncbi.nlm.nih.gov/pubmed/20842321 http://dx.doi.org/10.1100/tsw.2010.164 |
Ejemplares similares
-
Adenosine A(2A) receptors modulate BDNF both in normal conditions and in experimental models of Huntington’s disease
por: Potenza, R. L., et al.
Publicado: (2007) -
Adenosine A(2A) receptor inhibition reduces synaptic and cognitive hippocampal alterations in Fmr1 KO mice
por: Ferrante, Antonella, et al.
Publicado: (2021) -
Is the functional interaction between adenosine A(2A) receptors and metabotropic glutamate 5 receptors a general mechanism in the brain? Differences and similarities between the striatum and the hippocampus
por: Tebano, M. T., et al.
Publicado: (2006) -
P2X7 Receptor Agonist 2′(3′)-O-(4-Benzoylbenzoyl)ATP Differently Modulates Cell Viability and Corticostriatal Synaptic Transmission in Experimental Models of Huntington’s Disease
por: Martire, Alberto, et al.
Publicado: (2021) -
Adenosine A(2A) receptor stimulation restores cell functions and differentiation in Niemann-Pick type C-like oligodendrocytes
por: De Nuccio, Chiara, et al.
Publicado: (2019)