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Autophagy Regulates the Post-Translational Cleavage of BCL-2 and Promotes Neuronal Survival

B-cell lymphoma 2 protein (BCL-2) is one of the more widely investigated anti-apoptotic protein in mammals, and its levels are critical for protecting from programmed cell death. We report here that the cellular content of BCL-2 is regulated at post-translational level along the autophagy/lysosome p...

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Detalles Bibliográficos
Autores principales: Lossi, Laura, Gambino, Graziana, Salio, Chiara, Merighi, Adalberto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: TheScientificWorldJOURNAL 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5763967/
https://www.ncbi.nlm.nih.gov/pubmed/20495771
http://dx.doi.org/10.1100/tsw.2010.82