HIV-Specific CD8(+) T Cells Exhibit Reduced and Differentially Regulated Cytolytic Activity in Lymphoid Tissue

Elimination of lymphoid tissue reservoirs is a key component of HIV eradication strategies. CD8(+) T cells play a critical role in control of HIV, but their functional attributes in lymph nodes (LNs) remain unclear. Here, we show that memory, follicular CXCR5(+), and HIV-specific CD8(+) T cells from...

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Detalles Bibliográficos
Autores principales: Reuter, Morgan A., Del Rio Estrada, Perla M., Buggert, Marcus, Petrovas, Constantinos, Ferrando-Martinez, Sara, Nguyen, Son, Japp, Alberto Sada, Ablanedo-Terrazas, Yuria, Rivero-Arrieta, Amaranta, Kuri-Cervantes, Leticia, Gunzelman, Heidi M., Gostick, Emma, Price, David A., Koup, Richard A., Naji, Ali, Canaday, David H., Reyes-Terán, Gustavo, Betts, Michael R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5764192/
https://www.ncbi.nlm.nih.gov/pubmed/29262326
http://dx.doi.org/10.1016/j.celrep.2017.11.075

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5764192/
https://www.ncbi.nlm.nih.gov/pubmed/29262326
http://dx.doi.org/10.1016/j.celrep.2017.11.075

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