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The mitochondrial TMEM177 associates with COX20 during COX2 biogenesis

The three mitochondrial-encoded proteins, COX1, COX2, and COX3, form the core of the cytochrome c oxidase. Upon synthesis, COX2 engages with COX20 in the inner mitochondrial membrane, a scaffold protein that recruits metallochaperones for copper delivery to the Cu(A)-Site of COX2. Here we identified...

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Detalles Bibliográficos
Autores principales: Lorenzi, Isotta, Oeljeklaus, Silke, Aich, Abhishek, Ronsör, Christin, Callegari, Sylvie, Dudek, Jan, Warscheid, Bettina, Dennerlein, Sven, Rehling, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Pub. Co 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5764226/
https://www.ncbi.nlm.nih.gov/pubmed/29154948
http://dx.doi.org/10.1016/j.bbamcr.2017.11.010