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Trans10,cis12 conjugated linoleic acid inhibits proliferation and migration of ovarian cancer cells by inducing ER stress, autophagy, and modulation of Src

The goal of this study was to investigate the anti-cancer effects of Trans10,cis12 conjugated linoleic acid (t10,c12 CLA). MTT assays and QCM(™) chemotaxis 96-wells were used to test the effect of t10,c12 CLA on the proliferation and migration and invasion of cancer cells. qPCR and Western Blotting...

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Detalles Bibliográficos
Autores principales: Shahzad, Mian M. K., Felder, Mildred, Ludwig, Kai, Van Galder, Hannah R., Anderson, Matthew L., Kim, Jong, Cook, Mark E., Kapur, Arvinder K., Patankar, Manish S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5764254/
https://www.ncbi.nlm.nih.gov/pubmed/29324748
http://dx.doi.org/10.1371/journal.pone.0189524