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HIV-1 co-receptor tropism and liver fibrosis in HIV-infected patients

BACKGROUND: In vitro, gp120 of both X4 and R5 HIV-1 strains activates human hepatic stellate cells, but if it can promote liver fibrosis in vivo is unknown. We aimed to evaluate if patients carrying X4 or R5 strains have a different liver fibrosis (LF) progression over time. METHODS: A total of 1,13...

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Detalles Bibliográficos
Autores principales: Saracino, Annalisa, Cozzi-Lepri, Alessandro, Shanyinde, Milensu, Ceccherini Silberstein, Francesca, Nozza, Silvia, Di Biagio, Antonio, Cassola, Giovanni, Bruno, Giuseppe, Capobianchi, Maria, Puoti, Massimo, Monno, Laura, d’Arminio Monforte, Antonella
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5764264/
https://www.ncbi.nlm.nih.gov/pubmed/29324755
http://dx.doi.org/10.1371/journal.pone.0190302