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Exploring the binding sites and binding mechanism for hydrotrope encapsulated griseofulvin drug on γ-tubulin protein

The protein γ-tubulin plays an important role in centrosomal clustering and this makes it an attractive therapeutic target for treating cancers. Griseofulvin, an antifungal drug, has recently been used to inhibit proliferation of various types of cancer cells. It can also affect the microtubule dyna...

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Detalles Bibliográficos
Autores principales: Das, Shubhadip, Paul, Sandip
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5764265/
https://www.ncbi.nlm.nih.gov/pubmed/29324869
http://dx.doi.org/10.1371/journal.pone.0190209