Stage-specific IFN-induced and IFN gene expression reveal convergence of type I and type II IFN and highlight their role in both acute and chronic stage of pathogenic SIV infection

Interferons (IFNs) play a major role in controlling viral infections including HIV/SIV infections. Persistent up-regulation of interferon stimulated genes (ISGs) is associated with chronic immune activation and progression in SIV/HIV infections, but the respective contribution of different IFNs is u...

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Detalles Bibliográficos
Autores principales: Echebli, Nadia, Tchitchek, Nicolas, Dupuy, Stéphanie, Bruel, Timothée, Peireira Bittencourt Passaes, Caroline, Bosquet, Nathalie, Le Grand, Roger, Bourgeois, Christine, Favier, Benoit, Cheynier, Rémi, Lambotte, Olivier, Vaslin, Bruno
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5764266/
https://www.ncbi.nlm.nih.gov/pubmed/29324751
http://dx.doi.org/10.1371/journal.pone.0190334

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5764266/
https://www.ncbi.nlm.nih.gov/pubmed/29324751
http://dx.doi.org/10.1371/journal.pone.0190334

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