Safety of single low-dose primaquine in glucose-6-phosphate dehydrogenase deficient falciparum-infected African males: Two open-label, randomized, safety trials

BACKGROUND: Primaquine (PQ) actively clears mature Plasmodium falciparum gametocytes but in glucose-6-phosphate dehydrogenase deficient (G6PDd) individuals can cause hemolysis. We assessed the safety of low-dose PQ in combination with artemether-lumefantrine (AL) or dihydroartemisinin-piperaquine (D...

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Detalles Bibliográficos
Autores principales: Bastiaens, Guido J. H., Tiono, Alfred B., Okebe, Joseph, Pett, Helmi E., Coulibaly, Sam A., Gonçalves, Bronner P., Affara, Muna, Ouédraogo, Alphonse, Bougouma, Edith C., Sanou, Guillaume S., Nébié, Issa, Bradley, John, Lanke, Kjerstin H. W., Niemi, Mikko, Sirima, Sodiomon B., d’Alessandro, Umberto, Bousema, Teun, Drakeley, Chris
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5764271/
https://www.ncbi.nlm.nih.gov/pubmed/29324864
http://dx.doi.org/10.1371/journal.pone.0190272

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5764271/
https://www.ncbi.nlm.nih.gov/pubmed/29324864
http://dx.doi.org/10.1371/journal.pone.0190272

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