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The etomidate analog ET-26 HCl retains superior myocardial performance: Comparisons with etomidate in vivo and in vitro

OBJECTIVE: (R)-2-methoxyethyl1-(1-phenylethyl)-1H-imidazole-5-carboxylate hydrochloride (ET-26 HCl) is a novel etomidate analogue. The purpose of this study was to characterize whether ET-26 HCl could retain the superior myocardial performance of etomidate in vivo and in vitro. METHODS: In vivo, the...

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Detalles Bibliográficos
Autores principales: Liu, Xingxing, Song, Haibo, Yang, Jun, Zhou, Cheng, Kang, Yi, Yang, Linghui, Liu, Jin, Zhang, Wensheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5764323/
https://www.ncbi.nlm.nih.gov/pubmed/29324898
http://dx.doi.org/10.1371/journal.pone.0190994