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Serum galactose-deficient-IgA1 and IgG autoantibodies correlate in patients with IgA nephropathy

IgA nephropathy is an autoimmune disease characterized by IgA1-containing glomerular immune deposits. We previously proposed a multi-hit pathogenesis model in which patients with IgA nephropathy have elevated levels of circulatory IgA1 with some O-glycans deficient in galactose (Gd-IgA1, autoantigen...

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Detalles Bibliográficos
Autores principales: Placzek, William J., Yanagawa, Hiroyuki, Makita, Yuko, Renfrow, Matthew B., Julian, Bruce A., Rizk, Dana V., Suzuki, Yusuke, Novak, Jan, Suzuki, Hitoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5764330/
https://www.ncbi.nlm.nih.gov/pubmed/29324897
http://dx.doi.org/10.1371/journal.pone.0190967