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The B cell death function of obinutuzumab-HDEL produced in plant (Nicotiana benthamiana L.) is equivalent to obinutuzumab produced in CHO cells

Plants have attracted attention as bio-drug production platforms because of their economical and safety benefits. The preliminary efficacy of ZMapp, a cocktail of antibodies produced in N. benthamiana (Nicotiana benthamiana L.), suggested plants may serve as a platform for antibody production. Howev...

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Detalles Bibliográficos
Autores principales: Lee, Jin Won, Heo, Woon, Lee, Jinu, Jin, Narae, Yoon, Sei Mee, Park, Ki Youl, Kim, Eun Yu, Kim, Woo Taek, Kim, Joo Young
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5764350/
https://www.ncbi.nlm.nih.gov/pubmed/29324849
http://dx.doi.org/10.1371/journal.pone.0191075