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Age-related gene expression changes, and transcriptome wide association study of physical and cognitive aging traits, in the Lothian Birth Cohort 1936

Gene expression is influenced by both genetic variants and the environment. As individuals age, changes in gene expression may be associated with decline in physical and cognitive abilities. We measured transcriptome-wide expression levels in lymphoblastoid cell lines derived from members of the Lot...

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Detalles Bibliográficos
Autores principales: Harris, Sarah E., Riggio, Valentina, Evenden, Louise, Gilchrist, Tamara, McCafferty, Sarah, Murphy, Lee, Wrobel, Nicola, Taylor, Adele M., Corley, Janie, Pattie, Alison, Cox, Simon R., Martin-Ruiz, Carmen, Prendergast, James, Starr, John M., Marioni, Riccardo E., Deary, Ian J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5764388/
https://www.ncbi.nlm.nih.gov/pubmed/29207374
http://dx.doi.org/10.18632/aging.101333