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Human longevity: 25 genetic loci associated in 389,166 UK biobank participants

We undertook a genome-wide association study (GWAS) of parental longevity in European descent UK Biobank participants. For combined mothers' and fathers' attained age, 10 loci were associated (p<5*10(−8)), including 8 previously identified for traits including survival, Alzheimer's...

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Detalles Bibliográficos
Autores principales: Pilling, Luke C., Kuo, Chia-Ling, Sicinski, Kamil, Tamosauskaite, Jone, Kuchel, George A., Harries, Lorna W., Herd, Pamela, Wallace, Robert, Ferrucci, Luigi, Melzer, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5764389/
https://www.ncbi.nlm.nih.gov/pubmed/29227965
http://dx.doi.org/10.18632/aging.101334