A hypothesis-driven approach identifies CDK4 and CDK6 inhibitors as candidate drugs for treatments of adrenocortical carcinomas

High proliferation rate and high mutation density are both indicators of poor prognosis in adrenocortical carcinomas. We performed a hypothesis-driven association study between clinical features in adrenocortical carcinomas and the expression levels of 136 genes involved in DNA metabolism and G1/S p...

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Detalles Bibliográficos
Autores principales: Hadjadj, Djihad, Kim, Su-Jung, Denecker, Thomas, Driss, Laura Ben, Cadoret, Jean-Charles, Maric, Chrystelle, Baldacci, Giuseppe, Fauchereau, Fabien
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5764399/
https://www.ncbi.nlm.nih.gov/pubmed/29283884
http://dx.doi.org/10.18632/aging.101356

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5764399/
https://www.ncbi.nlm.nih.gov/pubmed/29283884
http://dx.doi.org/10.18632/aging.101356

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